The Institute for Biomedical Engineering, Science and Technology (iBEST) is a partnership between Ryerson University and St. Michael’s Hospital that brings together Ryerson’s engineering and science strengths with St. Michael’s biomedical research and clinical expertise to translate research concepts into testable healthcare solutions.

Located within the St. Michael’s Keenan Research Centre for Biomedical Science, iBEST’s access to biomedical, technological and clinical expertise allows its members and partners to identify challenges and rapidly pilot, modify and introduce biomedical discoveries and inventions to improve health.


  • Advance collaborative health research and development, and drive innovation through the widespread dissemination of research discoveries and findings and the creation of publications, patents, products and companies.
  • Deliver results for Ontario’s economy through the development of spin-off companies and the advancement of patient-centered solutions that reduce healthcare spending.
  • Provide world-class training to graduate students and research trainees and develop the next generation of innovators and multi-disciplinary talent.


Universities and hospitals play a critical role in driving innovation in healthcare.

Ryerson and St. Michael’s believe that innovation is borne from multidisciplinary collaboration. The institutions have a history of research collaborations, joint commercialization projects, and education and training opportunities dating back nearly two decades.

In 2013, Ryerson and St. Michael’s agreed on a 20-year partnership to launch iBEST with leadership from both institutions.

iBEST Executive Committee:


Dr. Steven N. Liss

Research and Innovation
Ryerson University

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Dr. Michael Benarroch

Provost and
Vice-President, Academic
Ryerson University

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Art Slutsky

Dr. Arthur Slutsky

Vice President of Research
St. Michael's Hospital

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iBEST Co-Directors:

Michael Kolios

Dr. Michael Kolios

Associate Dean,
Faculty of Science
Ryerson University

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Sri Krishnan

Dr. Sri Krishnan

Associate Dean,
Faculty of Engineering and Architectural Science
Ryerson University

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Ori Rotstein

Dr. Ori Rotstein

Keenan Research Centre for Biomedical Science
St. Michael's Hospital

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Research Themes

iBEST is built on a foundation of excellence that combines researcher expertise with state of the art labs and infrastructure. The Institute’s four main research areas drive discovery and foster alignment of R&D activities with market needs.

Biomedical Delivery Systems (BDS)

Theme Lead:
Dr. Scott Tsai

To maximize the effectiveness of medication and minimize undesirable side effects, researchers are experimenting with advanced delivery systems that improve the accuracy of therapeutic medicine and reduce healthcare costs. Applications of this research utilize various techniques, such as:

  • Microfluidics
  • Nanotechnology
  • Drug Delivery

Biomaterials, Tissue Injury & Repair (BTR)

Theme Lead:
Dr. Haibo Zhang

Researchers are creating new biomaterials and cell-based therapies to restore the structure and function of damaged tissues and organs. Researchers in this theme aim to:

  • Obtain a better understanding of cellular and molecular mechanisms of tissue injury and repair that can form the basis of designing new interventions that aid normal processes prevent pathological repair and restore tissue integrity following injury.
  • Treat injuries and diseases in ways that were previously unthinkable, such as growing a new kidney for a transplant patient or replacing knee cartilage for an arthritis sufferer.

Biomedical Imaging & Therapy (BIT)

Theme Lead:
Dr. General Leung

This rapidly advancing field has considerable potential for both diagnostic and treatment applications. Researchers are creating new approaches in a wide range of areas, such as:

  • Imaging at the cellular and tissue level for rapid diagnosis
  • Providing real-time feedback during surgery
  • Using image guided radiation therapy to target and kill cancer cells without patients having to enter an operating room.

Researchers are also using biomedical signal processing and mathematical modeling of physiological processes, in order to aid the development of:

  • Rapid disease diagnosis
  • Curb disease progression
  • Develop disease therapies

Healthcare Analytics & Applications (HAA)

Theme Lead:
Dr. Alireza Sadeghian

Researchers in this theme utilize high-performance computing and data analytic tools, to creating tools that improve our understanding and visualization of the massive amounts of healthcare data available, which have the potential to advance precision medicine. The aim of this type of research is to:

  • Provide new insights into the field of health care
  • Improve patient outcomes
  • Avoid unnecessary costs